The requirements for using 3D printers to fabricate functional prototypes, custom tooling and end-use parts in pre-clinical pharmaceutical and medical device applications are distinct from those of many other commercial applications. Whether you are producing parts for pre-clinical pharmaceutical applications in your AM lab, tool room or production floor, you need:
- Safe materials
- Parts that do not absorb water
- Parts with high chemical resistance
- Materials and parts that are low leaching and non-contaminating
- Elastomeric parts in some cases
- Traceable parts
- A range of complex geometries
If you are using AM for clinical applications, you need all of those capabilities, plus the printer must be safe to use outside the lab and parts must be able to be sterilized. In the case of Medical Device applications, not only do you require all of those capabilities, your parts must be strong enough to be used functionally.
Rize’s hybrid Augmented Polymer Deposition (APD) multi-material platform provides clear advantages for Life Sciences companies:
- Safety and security
- Isotropic strength and material and part performance
- Ink marking capability
- Low total cost of ownership
Safety and Security
Our APD process emits no VOCs and uses only safe and recyclable materials. Each component of our Rizium One material is USP Class VI Certified (FDA) and is non-contaminating.
Rize’s 3D printed ink marking capability enables you to print secure part numbers and instructions on your functional part. You can even print Digital Rights Management, in a QR code for example, right onto the part that creates an immutable digital thread to the digital twin of the physical 3D printed part on your platform.
Strength and Part Performance
Rize One produces either white or black parts with isotropic strength (uniform strength in X, Y and Z axes). Rizium One has less than 0.01% water absorption, low surface energy, a residual metals content of <0.02ppm and is resistant to chemicals like alcohol, acid and acetone. Rize parts can also be Gamma/Cold Sterilized.
Low Cost of Ownership
Since Rize One requires virtually no post-processing of parts following printing, you can get your parts >2X faster and 5-6X cheaper than other systems, while eliminating costly labor and equipment and time-consuming, messy and corrosive solvents.
Rize in use at Life Science Companies
Global medical device manufacturer, CONMED, uses Rize One to produce functional parts, such as handles for medical instrumentation, parts of assemblies and tooling for testing and to train doctors in CONMED’s world class cadaver lab. They also use Rize to produce functional prototypes throughout the iterative design, development and ergonomic testing process for new product development.
CONMED’s R&D test lab and model shop purchased a Rize One 3D printer for its part surface quality, ease of support removal, part strength and ink marking capability for printing part numbers onto parts. Saying that they purchased Rize One to be their “workhorse,” CONMED discovered they can successfully use Rize One to print molds for silicon and low-temperature plastic end-use parts in just one day. Since Rize parts have low surface energy, molded parts can be quickly and easily de-molded without the need for a release agent.
In fact, Rize is 30X faster and 30X cheaper than using traditional manufacturing methods to produce molds and 2X faster and 6X cheaper than extrusion-based 3D printers to produce molds. Rize molds can be reused repeatedly and include part numbers for versioning.
CONMED envisions using Rize’s newly announced Digitally Augmented Part capability to enhance their versioning capability. "Our process for the development of new products generally requires numerous iterations to get the part features just right," said David Perron, Group Manager at CONMED. "The changes are not always obvious, particularly when we're looking at dozens of iterations. The QR code will help us to easily identify iterations and show the flow of the design thought process."
Another global Life Sciences company needed a 3D printing solution that uses a safe material and process and provides a combination of chemical resistance, low moisture absorption, low surface energy and part strength for a number of functional applications that couldn’t be accomplished with their existing technology. They selected Rize One because, in addition to delivering those capabilities, Rize provides ink marking capability, as well as a one-touch user experience, including no post-processing after printing, which enables them to expand use of Rize 3D printing outside their lab into their scientists’ labs. The Company uses Rize One daily to produce end-use parts, including stirring units and impellers, nozzles and fixtures, as well as functional prototypes, including vessels, anatomical models for medication testing and more.
The Company’s Additive Manufacturing Engineer said, “We like to use Rize One as often as we can because it’s easy and reliable. Rize’s ease of use is a big plus compared to other 3D printers. It’s super easy to place and print a part with one click. There’s no need to export, file fixing and importing. The convenience factor of Rize’s zero-post-processing capability makes it easier to get to the final part.”